Wednesday, June 17, 2015

Drug Information Question

Question – Patient receives a prescription for Lamisil (terbinafine) 250mg for 10days and is inquiring when he may be allowed to drink alcohol again as he plans to attend a wedding on day 11.

Answer – Lamasil has a half-life of 22 to 26 hours with the half-life of 200 to 400 hours from skin and adipose tissue. Half-life is the amount of time needed to decrease the amount of drug in the body 50%. It usually takes 5 half-lives for the drug to be eliminated from the body close to 100%. With a half-life of 24 hours it would take approximately 5 days for terbinafine to be eliminated from the body. It would be best to wait 5 days before consuming alcohol after finishing the course of terbinafine. I called Novartis and they recommended not drinking alcohol with this product and they said they could not make a recommendation for after the patient stopped taking the medication.

Source:
Terbinafine hydrochloride.  DrugPoints Summary.  Micromedex 2.0.  Truven Health Analytics, Inc. Greenwood Village, CO.  Available at: http://www.micromedexsolutions.com.  Accessed June 16, 2015.


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