Zostavax, or the shingles vaccination, is stored frozen and needs to be reconstituted immediately once removed from the freezer. Once it is reconstituted it can appear hazy and off-white or pale yellow in color. It is administered as a single 0.65ml dose subcutaneously in the deltoid region of the upper arm. It needs to be administered within 30 minutes of being removed from the freezer. As of now it is scheduled for only a one time dose.
http://www.merck.com/product/usa/pi_circulars/z/zostavax/zostavax_pi2.pdf
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