Essential tremor (ET) is a common neurological disorder with a prevalence estimated of 5% world wide. The incidence of ET increases with age and has a big genetic component to it. ET is treated most effectively by primidone and propranolol. Primidone should be taken 12.5-25 mg/day at bedtime to start out. It can then be titrated up to 250 mg/day in 1 to 2 divided doses. Doses up to 750mg total per day may be beneficial in ET. Propranolol should be taken 40 mg twice daily to start out, but then increased to a usual maintenance dose of 120-320 mg/day in two divided doses. Common alternative treatments include atenolol, gabapentin, and topiramate.
Tarsy, Daniel. Overview of Tremor. UpToDate 2014.
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