The oral Typhoid Vaccine Vivotif for primary immunization should be taken one capsule on alternating days (day 1, 3, 5, 7) for 4 total doses. This should be completed at least one week prior to leaving on your trip. Capsules should be swallowed whole and taken with a glass of water one hour before a meal. Alcohol should be avoided one hour before or two hours after administration since it can disrupt the enteric coating. The capsules need to be stored in a refrigerator. If forgotten and left out of the fridge for less than 12 hours one time it is alright and can be taken regularly as long as they are kept in the fridge for the rest of the course. Once course is finished correctly, protection lasts for 5 years.
Vivotif (typhoid vaccine) [prescribing information]. Coral Gables, FL: Berna Products; August 2006
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