Sitavig (acyclovir buccal tablets) recently got released in North America for the treatment of recurrent cold sores. One tablet is placed on the upper lip at the first onset of symptoms and dissolves over a few hours. Sitavig is a potential alternative to current oral treatments (which usually last many doses over a few days) and other topical creams/ointments (which need to be reapplied several times a day).
http://sitavig.com/wp-content/uploads/2014/07/sitavig-prescribing-information_2014.pdf
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