Tuesday, July 21, 2015

Types of Insulin

Types of Insulin
v  Rapid-acting: Taken before a meal. Covers glucose elevations related to meals
o    Works in about 15 minutes and peaks at about 1 hour
o    Duration: 2 to 4 hours
o    Examples: Apidra (glulisine), Humalog (lispro), NovoLog (aspart)
o    Inhaled insulin: works in 15 minutes and peaks in 30 minutes. Out of system in 180 minutes
§  Afrezza
v  Short-acting: Taken before a meal. Covers glucose elevated related to meals
o    Works in 30 minutes and peaks in 2 to 3 hours
o    Duration: 3 to 6 hours
o    Examples: Humulin R and Novolin R
v  Intermediate-acting: Taken two times daily. Covers both meal and basal insulin needs
o    Works in 2 to 4 hours and peaks in 4 to 12 hours
o    Duration: 12 to 18 hours
o    Example: NPH (Humulin N, Novolin N)
v  Long-acting: Typically taking once daily (can be done twice daily). Meets basal insulin needs
o    Works in a few hours and covers insulin needs for 24 hours
o    Duration: 24 hours
o    Examples: Levemir (detemir) and Lantus (glargine)
v  Pre-mixed insulin: NPH with short or rapid-acting insulin
o    NPH/regular
§  70/30 (Humulin/Novolin) and 50/50 (Humulin)
o    Other pre-mixed insulin            
§  Novolog 70/30, Humalog 75/25, and Humalog 50/50
o    Ideal for patients with a consistent schedule
§  Same meal composition and activity level each day
§  Increase risk for hypoglycemia
§  Hard to adjust for changes in routine







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